Glycolytic regulatory enzyme PFKFB3 as a prognostic and tumor microenvironment biomarker in human cancers

作者：Qingen Da, Lei Huang, Can Huang, Ze’e Chen, Zhitong Jiang, Fang Huang, Tao Shen, Lu Sun, Zilong Yan, Xiaoqiang Ye, Jing Yi, Yu Huang, Jingjing Da, Mingming Ren, Jikui Liu, Tao Wang, Zhen Han, Kunfu Ouyang · 发表于：Aging · 年份：2023 · DOI：10.18632/aging.204758 · 被引用次数：14 · 研究领域：Cancer, Hypoxia, and Metabolism、Ferroptosis and cancer prognosis、Epigenetics and DNA Methylation

as a clinical risk factor, which has a good predictive ability. Our study indicated that PFKFB3 is a potent regulatory factor for TME and has the potential to be a valuable prognostic biomarker in human tumor therapy.