Left Bundle Branch Pacing Facilitated by Novel Surface Electrocardiography in Comparison with Electrophysiology Recording System

作者：Lan Su, Ling Zhu, Songjie Wang, Shengjie Wu, Xiao Chen, Zhouqing Huang, Liangping Wang, Lei Xu, Xiaohong Zhou, Weijian Huang · 发表于：medRxiv · 年份：2023 · DOI：10.1101/2023.05.22.23290368 · 被引用次数：4 · 研究领域：Cardiac pacing and defibrillation studies、Cardiac Arrhythmias and Treatments、ECG Monitoring and Analysis

Abstract Background Left bundle branch pacing (LBBP) had been proven to be feasible and safe in patients with a pacemaker indication. In this study, we assessed the feasibility and safety of LBBP procedure using simplified ECG monitoring and LBBP criteria in comparison with that by using the conventional EP system and currently adopted LBBP criteria. Methods The single-center study included 143 consecutive patients from March 2021 to January 2022. The operator was single-blind to the electrophysiology recording system (EP system), and only observed the electrophysiological characteristics of the four-lead ECG monitor and the pacing system analyzer (PSA) by naked eye. Other researchers kept synchronized records of the EP system, and analyzed whether the data were correct and consistent after the operation. Intraoperative data were collected and the safety of 3-month follow-up after operation were evaluated. Results Of 143 patients enrolled, 139 successfully performed LBBP, with a success rate of 97.2%, and the judgement concordance with EP system was 99.3%. The total operation time was 78.9±26.5min, the total fluoroscopy time was 9.5±6.1min, the fluoroscopy time of left bundle branch (LBB) lead deployment 3.0±2.6min, which had no significant difference with previous studies. Ventricular septal perforation occurred in 2 patients during the operation. Pacing parameters were stable and heart function improved during follow-up. Conclusions The simplified LBBP implantation method w...