New abietane and tigliane diterpenoids from the roots of Euphorbia fischeriana and their cytotoxic activities

作者：Xing-Mei Ma, Liang-Yue Mo, Zhao-Peng Ren, Xiaona Fan, Pinghua Sun, Hai‐Yan Tian, Ning Yang, Jiachen Zi · 发表于：Journal of Asian Natural Products Research · 年份：2023 · DOI：10.1080/10286020.2023.2197224 · 被引用次数：8 · 研究领域：Bioactive Natural Diterpenoids Research

Three new abietane and two new tigliane diterpenoids were isolated from the roots Euphorbia fischeriana. Their structures were elucidated by spectroscopic methods and quantum chemical calculation. Compounds 4 and 5 exhibited the inhibitory activities against human cancer cells HeLa and HepG2, with IC50 ranging from 3.54 to 11.45 µM.