Organic Afterglow Nanoparticles in Bioapplications

作者：Hengxin Shen, Shiyi Liao, Zhe Li, Youjuan Wang, Shuangyan Huan, Xiaobing Zhang, Guosheng Song · 发表于：Chemistry - A European Journal · 年份：2023 · DOI：10.1002/chem.202301209 · 被引用次数：26 · 研究领域：Nanoplatforms for cancer theranostics、Luminescence and Fluorescent Materials、Nicotinic Acetylcholine Receptors Study

Organic afterglow nanoparticles are unique optical materials that emit light long after cessation of excitation. Due to their advantages of no need for real-time light excitation, avoiding autofluorescence, low imaging background, high signal-to-background ratio, deep tissue penetration, and high sensitivity, afterglow imaging technology has been widely used in cell tracking, biosensing, cancer diagnosis, and cancer therapy, which provides an effective technical method for the acquisition of molecular information with high sensitivity, specificity and real-time at the cellular and living level. In this review, we summarize and illustrate the recent progress of organic afterglow imaging, focusing on the mechanism of organic afterglow materials and their biological application. Furthermore, we also discuss the potential challenges and the further directions of this field.