Photo- or Electrochemical Cyclization of Dienes with Diselenides to Access Seleno-Benzo[ b ]azepines

作者：Pengpeng Tan, Liwang Lu, Shilong Wang, Junxin Wang, Jia‐Yang Chen, Jia‐Yang Chen, Yijia Zhang, Lei Xie, Shubin Yang, Jinchun Chen, Jinchun Chen, Zhen Zhang · 发表于：The Journal of Organic Chemistry · 年份：2023 · DOI：10.1021/acs.joc.3c00475 · 被引用次数：22 · 研究领域：Organoselenium and organotellurium chemistry、Sulfur-Based Synthesis Techniques、Radical Photochemical Reactions

A cascade selenylation/cyclization of dienes with diselenides has been realized under visible-light irradiation or electrolysis conditions. Employing O 2 or electricity as a “green” oxidant, this protocol provides a green and efficient method for an array of biologically important seleno-benzo[ b ]azepine derivatives in moderate to good yields. The direct sunlight irradiation and gram-scale reaction render the approach practical and attractive.