Transcutaneous bilirubinometry versus total serum bilirubin measurement for newborns

作者：Charles I Okwundu, Abiola Olowoyeye, Olalekan A. Uthman, Johan Smith, Charles Shey Wiysonge, Vinod K. Bhutani, Michelle Fiander, Kanekal Suresh Gautham · 发表于：Cochrane Database of Systematic Reviews · 年份：2023 · DOI：10.1002/14651858.cd012660.pub2 · 被引用次数：45 · 研究领域：Neonatal Health and Biochemistry、Pediatric Hepatobiliary Diseases and Treatments、Gallbladder and Bile Duct Disorders

BACKGROUND: Jaundice is a very common condition in newborns, affecting up to 60% of term newborns and 80% of preterm newborns in the first week of life. Jaundice is caused by increased bilirubin in the blood from the breakdown of red blood cells. The gold standard for measuring bilirubin levels is obtaining a blood sample and processing it in a laboratory. However, noninvasive transcutaneous bilirubin (TcB) measurement devices are widely available and used in many settings to estimate total serum bilirubin (TSB) levels. OBJECTIVES: To determine the diagnostic accuracy of transcutaneous bilirubin measurement for detecting hyperbilirubinaemia in newborns. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, CINAHL and trial registries up to 18 August 2022. We also checked the reference lists of all included studies and relevant systematic reviews for other potentially eligible studies. SELECTION CRITERIA: We included cross-sectional and prospective cohort studies that evaluated the accuracy of any TcB device compared to TSB measurement in term or preterm newborn infants (0 to 28 days postnatal age). All included studies provided sufficient data and information to create a 2 × 2 table for the calculation of measures of diagnostic accuracy, including sensitivities and specificities. We excluded studies that only reported correlation coefficients. DATA COLLECTION AND ANALYSIS: Two review authors independently applied the eligibility criteria to all citations from the search and e...