Copper-Mediated Deconstructive Ring Cleavage of Cyclic Thioethers with Boron Compounds

作者：Guanyu Wang, Dongchang Han, Yue Li, Yangleiyu Nie, Selvaraj Muthusamy, Zhibin Luo, Bin Liu · 发表于：Organic Letters · 年份：2023 · DOI：10.1021/acs.orglett.3c01100 · 被引用次数：18 · 研究领域：Sulfur-Based Synthesis Techniques、Chemical Synthesis and Reactions、Catalytic C–H Functionalization Methods

The deconstructive ring cleavage of cyclic thioethers is achieved through a Chan-Lam type process with boron compounds. The sequential hydroboration/ring cleavage process from alkynes offered a new route to the preparation of vinyl sulfides based on the developed conditions. Further exploration has demonstrated the versatility of nucleophiles, delivering various functionalized sulfides featuring linear frameworks.