Association between different adiposity measures and all-cause mortality risk among centenarians: A prospective cohort study

作者：Shaohua Liu, Wenzhe Cao, Zhiqiang Li, Shengshu Wang, Shanshan Yang, Mingming Lu, Haowei Li, Yang Song, Shimin Chen, Xuehang Li, Rongrong Li, Jianhua Wang, Junhan Yang, Miao Liu, Yao He · 发表于：Clinical Nutrition · 年份：2023 · DOI：10.1016/j.clnu.2023.04.023 · 被引用次数：10 · 研究领域：Nutrition and Health in Aging、Health disparities and outcomes、Chronic Disease Management Strategies

IMPORTANCE: Little evidence on the association between adiposity measures and all-cause mortality was observed among centenarians, and no targeted development of optimal weight recommendations for them. OBJECTIVE: To comprehensively assess the association between adiposity indices and all-cause mortality among centenarians. DESIGN SETTING, AND PARTICIPANTS: This prospective population-based cohort study included 1002 centenarians registered in 18 counties and cities in Hainan Province from June 2014 to May 2021. The age of participants at baseline was provided by the civil affairs bureau and verified before enrollment. MAIN OUTCOMES AND MEASURES: All-cause mortality was rigorously confirmed as the primary outcome. BMI was calculated by height and weight. BRI was calculated by height and waist circumference. RESULTS: ) had lower mortality (hazard ratio [HR], 0.61; 95%CI, 0.47-0.79) (P for trend = 0.001). In BRI categories, compared with the lowest group (mean BRI = 2.3), the highest group (mean BRI = 5.7) had lower mortality (hazard ratio [HR], 0.66; 95%CI, 0.51-0.85) (P for trend = 0.002), and the risk did not decrease after BRI exceeded 3.9 in women. Higher BRI was associated with lower HRs after adjusting for interaction with comorbidities status. E-values analysis suggested robustness to unmeasured confounding. CONCLUSIONS AND RELEVANCE: BMI and BRI were inverse linear associated with mortality risk in the whole population, while BRI was observed to be J-shaped in women. T...