Human iPSC-derived midbrain organoids functionally integrate into striatum circuits and restore motor function in a mouse model of Parkinson's disease

作者：Xin Zheng, Deqiang Han, Weihua Liu, Xueyao Wang, Na Pan, Yuping Wang, Zhiguo Chen · 发表于：Theranostics · 年份：2023 · DOI：10.7150/thno.80271 · 被引用次数：64 · 研究领域：Pluripotent Stem Cells Research、Nerve injury and regeneration、Tissue Engineering and Regenerative Medicine

The findings of this study highlight the potential of hMOs as safe and efficacious donor graft sources for cell therapy to treat PD.