Oxidase-like Nanozyme Activity of Manganese Metal–Organic Framework Nanosheets for Colorimetric and Fluorescence Sensing of l -Cysteine

作者：Ajit Singh, Kriti Bijalwan, Neha Kaushal, Anu Kumari, Avishek Saha, Arindam Indra · 发表于：ACS Applied Nano Materials · 年份：2023 · DOI：10.1021/acsanm.3c01404 · 被引用次数：89 · 研究领域：Advanced Nanomaterials in Catalysis、Nanocluster Synthesis and Applications、Advanced biosensing and bioanalysis techniques

The utilization of ultrathin Mn-metal–organic framework (Mn-UMOF) nanosheets for oxidase-like nanozyme activity has been demonstrated. The Mn-UMOF exhibited superior nanozyme activity to oxidize chromogenic TMB and ABTS than the bulk Mn-BMOF. Based on this fact, a platform for the colorimetric sensing of l -cysteine ( l -cys) has been established over the detection of other amino acids and natural compounds such as urea and glucose. In addition, the Mn-UMOF has the capability of catalyzing the oxidation of amplex red to the fluorescent first oxidized product, which has been used to develop a fluorescence turn-off sensor for the selective sensing of l -cys.