Comparison of the upper airway morphology between Dutch and Chinese adults with obstructive sleep apnea

作者：Xiaoxin Shi, Hui Chen, Frank Lobbezoo, Jan de Lange, P.F. van der Stelt, Erwin Berkhout, Jing Guo, Shaohua Ge, Guoju Li, Yanzhong Li, Ghizlane Aarab · 发表于：Sleep And Breathing · 年份：2023 · DOI：10.1007/s11325-023-02834-z · 被引用次数：5 · 研究领域：Obstructive Sleep Apnea Research、Tracheal and airway disorders、Neuroscience of respiration and sleep

PURPOSE: The pathogenesis of obstructive sleep apnea (OSA) is complex and may vary between different races. It has been suggested that the anatomical balance between skeletal tissues and soft tissues around the upper airway is a key pathophysiologic factor of OSA. Therefore, the aim of this study was to compare the anatomical balance of the upper airway between Dutch and Chinese patients with OSA based on cone beam computed tomography (CBCT) images. METHODS: This was a cross-sectional study performed in two centers and included Dutch and Chinese adults with OSA. CBCT scans in the supine position were obtained for both Dutch and Chinese OSA groups. The primary outcome variable was the anatomical balance of the upper airway, defined as the ratio of the tongue area and the maxillomandibular enclosure area. RESULTS: , and AHI 16.5 ± 7.8 events/h). There were no significant differences in AHI, age, BMI, and sex between the two groups (P = 0.14-0.76). The Dutch group had a significantly larger tongue area and tongue length compared to the Chinese group (P = 0.01 and P < 0.01). On the other hand, the Chinese group had a smaller maxilla length compared to the Dutch group (P < 0.01). However, the anatomical balance of the upper airway of both groups was not significantly different (P = 0.16). CONCLUSION: Within the limitations of this study, no significant difference was found in the anatomical balance of the upper airway between Dutch and Chinese patients with mild to moderate OSA. T...