Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial

作者：Robin Kate Kelley, Makoto Ueno, Changhoon Yoo, Richard S. Finn, Junji Furuse, Zhenggang Ren, Thomas Yau, Heinz‐Josef Klümpen, Stephen L. Chan, Masato Ozaka, Chris Verslype, Mohamed Bouattour, Joon Oh Park, Olga Barajas, Uwe Pelzer, Juan W. Valle, Li Yu, Usha Malhotra, Abby B. Siegel, Julien Edeline, Arndt Vogel, Arndt Vogel, Mehmet Akce, Inmaculada Alés Díaz, Gustavo R. Alves, Sumitra Anand, Çağatay Arslan, Jamil Asselah, Eric Assenat, F. Aubin, Li‐Yuan Bai, Yuxian Bai, Olga Barajas, Susan E. Bates, Stephen Begbie, Irit Ben‐Aharon, Nina Beri, Marie‐Luise Berres, Jean‐Frédéric Blanc, Ivan Borbath, Robert Bordonaro, Mohamed Bouattour, Giovanni Brandi, Adam M. Burgoyne, Kritiya Butthongkomvong, Marcos Pedro Guedes Camandaroba, Ke Cao, Marcela Carballido, Jen‐Shi Chen, Jen‐Shi Chen, Ming-Huang Chen, Ashley Cheng, Ashley Cheng, Tai‐Jan Chiu, Hye Jin Choi, Hong Jae Chon, Joëlle Collignon, Antonio Cubillo Gracián, S. Lindsey Davis, Ricardo Saraiva de Carvalho, D.J.A. de Groot, Anne Demols, Judith de Vos, Maria Diab, Jacob C. Easaw, Martin Eatock, Julien Edeline, Rawad Elias, Fredericus Eskens, Alfredo Falcone, Plinio Fernández, Richard Finn, Fábio Franke, Masayuki Furukawa, Junji Furuse, Olumide B. Gbolahan, Karen Geboes, Keri-Lee Geneser, Zhimin Geng, Ravit Geva, Roopinder Gillmore, Thorsten Oliver Goetze, Hongfeng Gou, Julieta Grasselli, Shanzhi Gu, Mahmut Gümüş, Nadia Haj Mohammad, Chunyi Hao, Hakan Harputluoğlu, Hassan Hatoum, Volker Heinemann, Wang Kwong Ho, Chiun Hsu, Ayala Hubert, Jun‐Eul Hwang, Mevlüde İnanç, Soledad Iseas, Vaishnavi Jeyasingam, Paula Jiménez Fonseca, Warren Joubert, Jitlada Juengsamarn, Diego Kaen, Masashi Kanai, Stefan Kasper‐Virchow, Ghazaleh Kazemi, Fergal C. Kelleher, Robin Kelley, Jong Gwang Kim, Jin Won Kim, Ana Beatriz Kinupe Abrahão, Heinz Klumpen, Mark D. Kochenderfer, Fatih Köse, Ho Ching Lam, Choong‐kun Lee, Hyun Woo Lee, Myung Ah Lee, Margaret Lee, Wai Man Sarah Lee, Samuel Le Sourd, Dongliang Li, Wěi Li, Houjie Liang, Tingbo Liang, Chun Sen Lim, Brian M. Lingerfelt, Charles D. Lopez, J.N. Low, T. Macarulla Mercadé, David Malka, Yimin Mao, Gianluca Masi, Steven McCune, Ray McDermott, Elaine McWhirter, Guillermo Méndez, Michèle Milella, Nobumasa Mizuno, Tomonori Mizutani, Camila Motta Venchiarutti Moniz, Luisa Morales, Andrés J. Muñoz Martín, Bruno Nervi, Nuttapong Ngamphaiboon, Sang Cheul Oh, Berna Öksüzoğlu, Darryl Outlaw, Masato Ozaka, Mustafa Özgüroğlu, Özgür Özyılkan, Claudio Painemal, Yueyin Pan, Joon Oh Park, Uwe Pelzer, Chuang Peng, Caroline Pétorin, Denis Pezet, Derek G. Power, Shukui Qin, Zhenggang Ren, Aflah Roohullah, Hyewon Ryu, Pamela Salman, Mitsuhito Sasaki, Rita Sasidharan, Taroh Satoh, Kornelius Schulze, Martin Scott-Brown, Ruben Segovia, Thomas Seufferlein, Salvatore Siena, Isabelle Sinapi, Cristina Smolenschi, Tianqiang Song, Aumkhae Sookprasert, Nopadol Soparattanapaisarn, Naureen Starling, Stacey Stein, Salomon M. Stemmer, Haichuan Su, Rie Sugimoto, Thatthan Suksombooncharoen, Vincent C. Tam, Ai Lian Tan, Chih Kiang Tan, Suebpong Tanasanvimon, Giuseppe Tonini, Giampaolo Tortora, Akihito Tsuji, Makoto Ueno, Rodrigo Uribe-Pacheco, Marino Venerito, Helena Verdaguer Mata, Chris Verslype, Ana Paula Victorino, Arndt Vogel, Arndt Vogel, James C. Wade, Dirk Waldschmidt, Lu Wang, Wan Zamaniah Wan Isahk, H.S. Wasan, Rui Weschenfelder, Chun Yin Wong, Yoke Fui Wong, Şuayib Yalçın, Patricio Yañez Weber, Xuezhong Yang, Hisateru Yasui, Thomas Yau, Ozan Yazıcı, Chia‐Jui Yen, Jieer Ying, Changhoon Yoo, Wenchang Yu, Haitao Zhao · 发表于：The Lancet · 年份：2023 · DOI：10.1016/s0140-6736(23)00727-4 · 被引用次数：1092 · 研究领域：Cholangiocarcinoma and Gallbladder Cancer Studies、Gallbladder and Bile Duct Disorders、Liver Diseases and Immunity