Outcomes of Partial Versus Complete Goniotomy With or Without Phacoemulsification for Primary Open Angle Glaucoma: A Multicenter Study

作者：Yunhe Song, Xiaomin Zhu, Yao Zhang, Jing Shu, Guangfu Dang, Wenzong Zhou, Lu Sun, Fei Li, Fengbin Lin, Yingzhe Zhang, Xiaohong Liang, Zhenyu Wang, Yi Zhang, Yu Zhang, Weirong Chen, Liuzhi Zeng, Li Tang, Lin Xie, Dennis S.C. Lam, Ningli Wang, Keith Barton, Robert N. Weinreb, Xiulan Zhang, PVP study group · 发表于：Journal of Glaucoma · 年份：2023 · DOI：10.1097/ijg.0000000000002210 · 被引用次数：41 · 研究领域：Glaucoma and retinal disorders、Corneal surgery and disorders、Retinal and Macular Surgery

PRÉCIS: Goniotomy (GT) 120 degrees with or without phacoemulsification was sufficient to lower the intraocular pressure (IOP) and reduce hyphema for primary open angle glaucoma. PURPOSE: To compare the surgical outcomes and safety profiles of 120 degrees and 360 degrees GT with or without phacoemulsification cataract extraction and intraocular lens implantation (PEI) for primary open angle glaucoma. PATIENTS AND METHODS: This multicenter retrospective study consisted of 139 eyes and was divided into 4 groups: (1) 120 degrees GT, (2) 360 degrees GT, (3) PEI + 120 degrees GT, and (4) PEI + 360 degrees GT. IOP, number of topical hypotensive medications, and complications were recorded and evaluated at baseline and at the final visit. The complete and qualified success rate and their potential associated factors were also investigated. The effectiveness and safety profile of the surgery were compared between different subgroups. RESULTS: After a mean follow-up of 8.6 months, the IOP reduction was 13.2 ± 8.3 (38.8 ± 28.8%), 12.4 ± 8.3 (41.6 ± 18.2%), 12.8 ± 9.9 (39.4 ± 34.5%), and 13.8 ± 7.2 (46.0±17.1%) mm Hg in 120 degrees, 360 degrees, PEI + 120 degrees GT group, and PEI + 360 degrees GT, respectively. No significant difference was found in IOP, a decline of IOP from baseline, topical hypotensive medication, and complete or qualified success between either standalone 120 degrees versus 360 degrees GT, or PEI + 120 degrees versus PEI + 360 degrees GT (all P s > 0.05). The PEI + ...