Factors influencing treatment status of syphilis among pregnant women: a retrospective cohort study in Guangzhou, China

作者：Huihui Liu, Niannian Chen, Weiming Tang, Songying Shen, Jia Yu, Huiyun Xiao, Xingwen Zou, Jianrong He, Joseph D. Tucker, Xiu Qiu · 发表于：International Journal for Equity in Health · 年份：2023 · DOI：10.1186/s12939-023-01866-x · 被引用次数：13 · 研究领域：Syphilis Diagnosis and Treatment、Reproductive tract infections research、HIV/AIDS Research and Interventions

BACKGROUND: Many syphilis infected pregnant women do not receive treatment, representing a major missed opportunity to reduce the risk of syphilis-related adverse pregnancy outcomes. This study explored correlates of treatment among pregnant women with syphilis in Guangzhou, China. METHODS: Pregnant women with a diagnosis of syphilis in Guangzhou between January 2014 and December 2016 were included. Information of syphilis treatment and correlates were extracted from a comprehensive national case-reporting system. Multivariate logistic regression was used to identify the correlations between information on the demographic characteristics, previous history, clinical characteristics about current syphilis, information of diagnosing hospital, and receiving no treatment or inadequate treatment among syphilis-seropositive pregnant women. A causal mediation analysis was used to explore the potential mediating role of the timing of syphilis diagnosis in the correlates. RESULTS: Among 1248 syphilis-seropositive pregnant women, 379 (30.4%) women received no treatment or inadequate treatment. Migrant pregnant women (adjusted OR = 1.83, 95% CI: 1.25-2.73), multiparous participants (adjusted OR = 3.68, 95% CI: 2.51-5.50), unmarried participants (adjusted OR = 3.21, 95% CI: 1.97-5.28) and unemployed participants (adjusted OR = 2.43, 95% CI: 1.41-4.39) were more likely to receive no treatment or inadequate treatment. Participants who with history of syphilis infection (adjusted OR = 0.59, ...