Comprehensive profiling of serotypes, antimicrobial resistance and virulence of Salmonella isolates from food animals in China, 2015–2021

作者：Lili Guo, Tianan Xiao, Liqin Wu, Yan Li, Xiaoxiao Duan, Wenhua Liu, Kaidi Liu, Wenjie Jin, Hao Ren, Jian Sun, Yahong Liu, Xiao‐Ping Liao, Yongda Zhao · 发表于：Frontiers in Microbiology · 年份：2023 · DOI：10.3389/fmicb.2023.1133241 · 被引用次数：31 · 研究领域：Salmonella and Campylobacter epidemiology、Vibrio bacteria research studies、Listeria monocytogenes in Food Safety

Introduction Salmonella is a ubiquitous foodborne pathogen and mainly transmitted to human farm-to-fork chain through contaminated foods of animal origin. Methods In this study, we investigated the serotypes, antimicrobial resistance and virulence of Salmonella from China. Results A total of 617 Salmonella isolates were collected from 4 major food animal species across 23 provi nces in China from 2015-2021. Highest Salmonella prevalence were observed in Guangdong (44.4%) and Sandong (23.7%). Chickens (43.0%) was shown to be the major source of Salmonella contamination, followed by pigs (34.5%) and ducks (18.5%). The number of Salmonella increased significantly from 5.51% to 27.23% during 2015–2020. S . Derby (17.3%), S . Enteritidis (13.1%) and S . Typhimurium (11.4%) were the most common serotypes among 41 serotypes identifiedin this study. Antibiotic susceptibility testing showing that the majority of the Salmonella isolates were resistant to neomycin (99.7%), tetracycline (98.1%), ampicillin (97.4%), sulfadiazine/trimethoprim (97.1%), nalidixic acid (89.1%), doxycycline (83.1%), ceftria xone (70.3%), spectinomycin (67.7%), florfenicol (60.0%), cefotaxime (52.0%) and lomefloxacin (59.8%). The rates of resistance to multiple antibiotics in S . Derby and S .Typhimurium were higher than that in S . Enteritidis. However, the rate of resistance to fosfomycin were observed from higher to lower by S . Derby, S . Enteritidis, and S . Typhimurium. Biofilm formation ability analysis ...