Photoredox Synthesis of Thio‐Functionalized Cyclic Ethers Using N ‐Sulfenyl Phthalimides as a Thiyl‐Radical Precursor

作者：Maojian Lu, Rong‐Bin Liang, Can‐Ming Zhu, Qing‐Xiao Tong, Jian‐Ji Zhong · 发表于：Chinese Journal of Chemistry · 年份：2023 · DOI：10.1002/cjoc.202300118 · 被引用次数：20 · 研究领域：Sulfur-Based Synthesis Techniques、Radical Photochemical Reactions、Catalytic C–H Functionalization Methods

Comprehensive Summary A visible‐light mediated exclusively regioselective synthesis of 2,2‐disubstituted thio‐functionalized tetrahydrofurans, tetrahydro‐ pyrans and oxepanes has been described through an operationally simple and mild photoredox protocol. Thiyl radical generated from N ‐phenylsulfenyl phthalimide by photoredox catalysis was proven to be the key reactive intermediate in this reaction.