Diffuse gastric polyposis in a young patient with a giant retroperitoneal mass: A case report

作者：Guangbing Duan, Huihui Sun, Ye Chen, Junwen Wang, Yu Zeng, Shurong Ji, Jie Xiong, Ying Chen, Wenfang Liu, Shuchang Xu · 发表于：Experimental and Therapeutic Medicine · 年份：2023 · DOI：10.3892/etm.2023.11925 · 研究领域：Gastrointestinal Tumor Research and Treatment、Genetic factors in colorectal cancer、Gastrointestinal disorders and treatments

Familial adenomatous polyposis (FAP) is characterized by hundreds of colonic adenomatous polyps and extraintestinal manifestations beginning in adolescence and early adulthood. It is also one of the most common hereditary colorectal cancer syndromes. In this case study, a rare phenotype of FAP associated with diffuse gastric polyposis, colon oligo-polyposis, and a massive retroperitoneal mass is described. The results expand on the current body of knowledge of FAP and may represent a new phenotypic expression of FAP. Accurate evidence-based surveillance and management recommendations for this disease require further research and evaluation.