Recent Advances in Transition Metal-Catalyzed B—H Bond Activation for Synthesis of o-Carborane Derivatives with B—Heteroatom Bond

作者：Hairui Jia, Zaozao Qiu · 发表于：Chinese Journal of Organic Chemistry · 年份：2023 · DOI：10.6023/cjoc202211040 · 被引用次数：5 · 研究领域：Boron Compounds in Chemistry、Radiopharmaceutical Chemistry and Applications、Organoboron and organosilicon chemistry

Carboranes are a class of carbon-boron molecular clusters with exceptional thermal and chemical stabilities.They are finding a variety of applications in medicine, materials, and coordination/organometallic chemistry as functional building blocks.Recently, transition metal catalyzed regioselective o-carborane B-H activation has been rapidly developed, offering a series of novel methodologies for selective cage boron functionalization.The current state of functionalization of o-carboranes to form B-B, B-N, B-O, B-S, and B-halogen bonds using transition metal-catalyzed B-H activation strategy is summarized.Some reaction mechanisms are highlighted, and the future challenges and focus of the carborane B-heteroatom bond construction are discussed.