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Synthesis and anticancer mechanisms of zinc( ii )-8-hydroxyquinoline complexes with 1,10-phenanthroline ancillary ligands

作者:Ling-Qi Du, Tianyu Zhang, Xiaomei Huang, Yue Xu, Ming‐Xiong Tan, Yan Huang, Yuan Chen, Qi‐Pin Qin · 发表于:Dalton Transactions · 年份:2023 · DOI:10.1039/d3dt00150d · 被引用次数:31 · 研究领域:Metal complexes synthesis and properties、Metal-Organic Frameworks: Synthesis and Applications、Lanthanide and Transition Metal Complexes

DQ1–DQ20 exhibit selective cytotoxicity to SK-OV-3/DDP. They inhibit cell growth via mitophagy pathways. Importantly, DQ6 displays high in vivo antitumor activity.