Comparison of mental health symptoms before and during the covid-19 pandemic: evidence from a systematic review and meta-analysis of 134 cohorts

作者：Ying Sun, Yin Wu, Suiqiong Fan, Tiffany Dal Santo, Letong Li, Xiaowen Jiang, Kexin Li, Yutong Wang, Amina Tasleem, Ankur Krishnan, Chen He, Olivia Bonardi, Jill T Boruff, Danielle Brittany Rice, Sarah Markham, Brooke Levis, Marleine Azar, Ian Thombs-Vite, Dipika Neupane, Branka Agic, Christine Fahim, Michael S. Martin, Sanjeev Sockalingam, Gustavo Turecki, Andrea Benedetti, Brett D. Thombs · 发表于：BMJ · 年份：2023 · DOI：10.1136/bmj-2022-074224 · 被引用次数：291 · 研究领域：COVID-19 and Mental Health、Long-Term Effects of COVID-19、COVID-19 and healthcare impacts

OBJECTIVE: To synthesise results of mental health outcomes in cohorts before and during the covid-19 pandemic. DESIGN: Systematic review. DATA SOURCES: Medline, PsycINFO, CINAHL, Embase, Web of Science, China National Knowledge Infrastructure, Wanfang, medRxiv, and Open Science Framework Preprints. ELIGIBILITY CRITERIA FOR SELECTING STUDIES: Studies comparing general mental health, anxiety symptoms, or depression symptoms assessed from 1 January 2020 or later with outcomes collected from 1 January 2018 to 31 December 2019 in any population, and comprising ≥90% of the same participants before and during the covid-19 pandemic or using statistical methods to account for missing data. Restricted maximum likelihood random effects meta-analyses (worse covid-19 outcomes representing positive change) were performed. Risk of bias was assessed using an adapted Joanna Briggs Institute Checklist for Prevalence Studies. RESULTS: 0.11, 95% confidence interval -0.00 to 0.22) or anxiety symptoms (0.05, -0.04 to 0.13), but depression symptoms worsened minimally (0.12, 0.01 to 0.24). Among women or female participants, general mental health (0.22, 0.08 to 0.35), anxiety symptoms (0.20, 0.12 to 0.29), and depression symptoms (0.22, 0.05 to 0.40) worsened by minimal to small amounts. In 27 other analyses across outcome domains among subgroups other than women or female participants, five analyses suggested that symptoms worsened by minimal or small amounts, and two suggested minimal or small imp...