α-C–H functionalization of glycine derivatives under mechanochemical accelerated aging en route the synthesis of 1,4-dihydropyridines and α-substituted glycine esters

作者：Keyu Xiang, Ping Ying, Ying Tao, Weike Su, Jingbo Yu · 发表于：Green Chemistry · 年份：2023 · DOI：10.1039/d3gc00538k · 被引用次数：20 · 研究领域：Catalytic C–H Functionalization Methods、Phenothiazines and Benzothiazines Synthesis and Activities、Chemical Synthesis and Analysis

A novel accelerated aging cross dehydrogenative coupling of glycine esters/amides and various nucleophiles under metal-free and solvent-minimal conditions was developed, providing a sustainable strategy to the synthesis of 1,4-DHP and α-substituted glycine derivatives.