Relationship between night-sleep duration and risk for depression among middle-aged and older people: A dose–response meta-analysis

作者：Xinlin Li, Jiayin Wei, Xinying Zhang, Zhuo Meng, Wentao Zhu · 发表于：Frontiers in Physiology · 年份：2023 · DOI：10.3389/fphys.2023.1085091 · 被引用次数：54 · 研究领域：Sleep and related disorders、Sleep and Work-Related Fatigue、Circadian rhythm and melatonin

Objective: The study aimed to examine the dose–response associations between night-sleep duration and depression risk in middle-aged and older adults. Methods: We searched PubMed, Embase, Web of Science, CNKI, VIP, and the Wanfang data knowledge service platforms from inception to 31 July 2022. Cohort and case–control studies assessing the relationship between night-sleep duration and depression were selected. We used the Newcastle–Ottawa scale to assess the quality of the published research. Two researchers carried out data extraction and quality assessment. The restricted cubic spline function and generalized least squares method were used to establish dose–response relationships between sleep duration and depression. We aimed to analyze the estimated effect size presented as the risk ratio (RR) and its 95% confidence interval (CI) using Stata 12.0. Result: Six cohort studies with 33,595 participants were included in this meta-analysis. A U-shaped association between sleep duration and depression risk was revealed. On one hand, compared with 7-h of night sleep, both shorter and longer sleep duration were associated with an increased risk of depression (5 h: risk ratio = 1.09, 95% confidence interval = 1.07–1.12; 6 h: RR = 1.03, 95% CI = 1.02–1.04; 8 h: RR = 1.10, 95% CI = 1.05–1.15; 9 h: RR = 1.31, 95% CI = 1.17–1.47; 10 h: RR = 1.59, 95% CI = 1.31–1.92; non-linear test p < 0.05). On the other hand, an increased risk of depression with shorter sleep duration was obse...