Estimated Burden of Stroke in China in 2020

作者：Wen‐Jun Tu, Zhenping Zhao, Peng Yin, Lei Cao, Jingsheng Zeng, Dawei Chen, Dongsheng Fan, Qi Fang, Pei Gao, Yuxiang Gu, Guo-Jun Tan, Jianfeng Han, Li He, Bo Hu, Hua Yang, Dezhi Kang, Hongyan Li, Jianmin Liu, Yuanli Liu, Min Lou, Benyan Luo, Suyue Pan, Bin Peng, Lijie Ren, Lihua Wang, Jian Wu, Yuming Xu, Yun Xu, Yi Yang, Meng Zhang, Shu Zhang, Liangfu Zhu, Yi‐Cheng Zhu, Zixiao Li, Lan Chu, Xiuli An, Lingxiao Wang, Meng Yin, Mei Li, Li Yin, Wei Qi Yan, Chuan Li, Junli Tang, Maigeng Zhou, Longde Wang · 发表于：JAMA Network Open · 年份：2023 · DOI：10.1001/jamanetworkopen.2023.1455 · 被引用次数：594 · 研究领域：Acute Ischemic Stroke Management、Intracerebral and Subarachnoid Hemorrhage Research、Neurological Disease Mechanisms and Treatments

Importance: Stroke is the leading cause of death in China. However, recent data about the up-to-date stroke burden in China are limited. Objective: To investigate the urban-rural disparity of stroke burden in the Chinese adult population, including prevalence, incidence, and mortality rate, and disparities between urban and rural populations. Design, Setting, and Participants: This cross-sectional study was based on a nationally representative survey that included 676 394 participants aged 40 years and older. It was conducted from July 2020 to December 2020 in 31 provinces in mainland China. Main Outcomes and Measures: Primary outcome was self-reported stroke verified by trained neurologists during a face-to-face interviews using a standardized protocol. Stroke incidence were assessed by defining first-ever strokes that occurred during 1 year preceding the survey. Strokes causing death that occurred during the 1 year preceding the survey were considered as death cases. Results: The study included 676 394 Chinese adults (395 122 [58.4%] females; mean [SD] age, 59.7 [11.0] years). In 2020, the weighted prevalence, incidence, and mortality rates of stroke in China were 2.6% (95% CI, 2.6%-2.6%), 505.2 (95% CI, 488.5-522.0) per 100 000 person-years, and 343.4 (95% CI, 329.6-357.2) per 100 000 person-years, respectively. It was estimated that among the Chinese population aged 40 years and older in 2020, there were 3.4 (95% CI, 3.3-3.6) million incident cases of stroke, 17.8 (95% CI...