National Brain Tumour Registry of China (NBTRC) statistical report of primary brain tumours diagnosed in China in years 2019–2020

作者：Dan Xiao, Changxiang Yan, Deling Li, Tianshu Xi, Xianzhi Liu, Dan Zhu, Guodong Huang, Jianguo Xu, Zhengwen He, Anhua Wu, Chiyuan Ma, Jiang Long, Kai Shu, Hongming Ji, Ning Wang, Gang Chen, Jiankai Yang, Hui Ma, Zhiyong Li, Xiaochuan Sun, Yan Qu, Zhixiong Liu, Xiaofan Jiang, Chunlei Tian, Shilei Ni, Renya Zhan, Liwen Chen, Ming Ge, Maode Wang, Xiaobing Jiang, Geng Guo, Zhenmin Han, Chuan Zhang, Tingrong Zhang, Changwu Dou, Liangzhao Chu, Pengcheng Wang, J.F. Shao, Xiyue Wu, Ju Yu, Yu Wang, Nan Wu, Rui Zhang, Mingming Zhang, Yong Kil Hong, Jianzhong Gao, Yunqian Li, Yawen Pan, Bing Zhao, Nan Ji, Guangliang Shan, Chirag B. Patel, Wang Jia, Liwei Zhang · 发表于：The Lancet Regional Health - Western Pacific · 年份：2023 · DOI：10.1016/j.lanwpc.2023.100715 · 被引用次数：25 · 研究领域：Glioma Diagnosis and Treatment、Brain Metastases and Treatment、Meningioma and schwannoma management

Background The lack of a well-designed brain tumour registry with standardized pathological diagnoses in underdeveloped countries hinders the ability to compare epidemiologic data across the globe. The National Brain Tumour Registry of China (NBTRC), created in January 2018, is the first multi-hospital-based brain tumour registry in China. Patient data reported to the NBTRC in years 2019–2020 were assessed. Methods Tumour pathology was based on the 2016 World Health Organization (WHO) classification of tumours of the central nervous system and ICD-O-3. The anatomical site was coded per the Surveillance, Epidemiology, and End Results (SEER) solid tumour module (version of July 2019). The cases were tabulated by histology and anatomical site. Categorical variables were reported as numbers (percentages). The distribution of tumours by age (0–14, 15–19, 20–39, 40–64, and 65+ years) was analysed. Findings There were a total of 25,537 brain tumours, foremost among them meningioma (23.63%), followed by tumours of the pituitary (23.42%), and nerve sheath tumours (9.09%). Glioblastoma, the most common and lethal form of primary brain cancer in adults, represented 8.56% of all cases. Of note, 6.48% of the malignant tumours were located in the brain stem. The percentage of malignant brain tumours decreased with increasing age, 24.08% in adults (40+ years), 30.25% in young adults (20–39 years), 35.27% in adolescents (15–19 years), and 49.83% in children (0–14 years). Among the 2107 paedi...