Ultrasensitive determination of α-glucosidase activity using CoOOH nanozymes and its application to inhibitor screening

作者：Demiao Ma, Jia Ge, Ang Wang, Jingxian Li, Hongfen Yang, Wenlei Zhai, Ren Cai · 发表于：Journal of Materials Chemistry B · 年份：2023 · DOI：10.1039/d2tb02580a · 被引用次数：18 · 研究领域：Advanced Nanomaterials in Catalysis、Advanced biosensing and bioanalysis techniques、Electrochemical sensors and biosensors

. Furthermore, the designed sensing platform exhibits favorable applicability for the α-glucosidase (α-Glu) activity assay in real samples. Meanwhile, this method can be expanded to study the inhibitors of α-Glu. Finally, the as-proposed method combined with a smartphone would be a color recognizer, which was successfully applied for the determination of α-Glu activity in human serum samples.