Supramolecular detoxification of nitrogen mustard via host–guest encapsulation by carboxylatopillar[5]arene

作者：Siyuan Zhou, Yi Chen, Jie Xu, Yongfei Yin, Jianqing Yu, Wei Liu, Shigui Chen, Lu Wang · 发表于：Journal of Materials Chemistry B · 年份：2023 · DOI：10.1039/d2tb02211g · 被引用次数：18 · 研究领域：Supramolecular Chemistry and Complexes、Molecular Sensors and Ion Detection、Porphyrin and Phthalocyanine Chemistry

experiments also indicated that the toxicity of the aziridinium salt (2) is inhibited with the formation of a stable host-guest complex, and CP[5]AK has a good therapeutic effect on the damage caused by NM. This study provides a new mechanism and strategy for the treatment of NM exposure-induced skin injuries.