Evaluation of Children with Malignancies for Blood and Marrow Transplantation: A Report from the ASTCT Committee on Practice Guidelines

作者：Ellen Fraint, Hisham Abdel‐Azim, Neel S. Bhatt, Larisa Broglie, Asma Chattha, Mira A. Kohorst, Yiouli P. Ktena, Michelle A. Lee, Susan E. Long, Muna Qayed, Akshay Sharma, Heather E. Stefanski, Anant Vatsayan, Lisa Wray, Mehdi Hamadani, Paul A. Carpenter · 发表于：Transplantation and Cellular Therapy · 年份：2023 · DOI：10.1016/j.jtct.2023.02.003 · 被引用次数：14 · 研究领域：Childhood Cancer Survivors' Quality of Life、Acute Lymphoblastic Leukemia research、Hematopoietic Stem Cell Transplantation

Evaluation of a candidate for hematopoietic cell transplantation (HCT) is a complex process with substantial intercenter variability. Although literature providing guidance for evaluating the eligibility of adults is well established, similar guidance for children is lacking. To address gaps between adult recommendations and the specific needs of children, we convened a panel of pediatric HCT experts from a wide geographic range of American Society of Transplantation and Cellular Therapy (ASTCT) member institutions to offer recommendations for pediatric-focused pre-HCT evaluation. In this report from the ASTCT Committee on Practice Guidelines, we present a practical framework for evaluating children with malignancies who are candidates for HCT. We also highlight key differences from adults and emphasize areas of unmet need that require additional research to delineate best practices.