Simple Ether‐Directed Enantioselective C( sp 3 )−H Borylation of Cyclopropanes Enabled by Iridium Catalysis

作者：Tian Xie, Lili Chen, Zhenlu Shen, Senmiao Xu · 发表于：Angewandte Chemie International Edition · 年份：2023 · DOI：10.1002/anie.202300199 · 被引用次数：46 · 研究领域：Catalytic C–H Functionalization Methods、Cyclopropane Reaction Mechanisms、Asymmetric Hydrogenation and Catalysis

Abstract Reported here is an efficient and simple ether‐directed iridium‐catalyzed enantioselective C( sp 3 )−H borylation of cyclopropanes. Various functional groups were well‐tolerated, affording a vast array of chiral cyclopropanes with high enantioselectivities. We also demonstrated that the turnover numbers of the current reaction could be up to 335.