Global reporting of progress towards elimination of hepatitis B and hepatitis C
作者：Fuqiang Cui, Sarah Blach, Casimir Manzengo Mingiedi, Mónica Alonso González, Ahmed Sabry Alaama, Antons Mozalevskis, Nicole Seguy, Bharat Bhushan Rewari, Polin Chan, Linh‐Vi Le, Meg C. Doherty, Niklas Luhmann, Philippa Easterbrook, Mae Ashworth Dirac, Catherine de Martel, Shevanthi Nayagam, Timothy B. Hallett, Peter T. Vickerman, Homie A. Razavi, Olufunmiayo Lesi, Daniel Low‐Beer · 发表于：The Lancet. Gastroenterology & hepatology · 年份：2023 · DOI：10.1016/s2468-1253(22)00386-7 · 被引用次数：335 · 研究领域：Hepatitis B Virus Studies、Hepatitis C virus research、Hepatitis Viruses Studies and Epidemiology
BACKGROUND: The 69th World Health Assembly endorsed the global health sector strategy on viral hepatitis to eliminate viral hepatitis as a public health threat by 2030. Achieving and measuring the 2030 targets requires a substantial increase in the capacity to test and treat viral hepatitis infections and a mechanism to monitor the progress of hepatitis elimination. This study aimed to identify the gaps in data availability or quality and create a new mechanism to monitor the progress of hepatitis elimination. METHODS: In 2020, using a questionnaire, we collected empirical, systematic, modelled, or surveyed data-reported by WHO country and WHO regional offices-on indicators of progress towards elimination of viral hepatitis, including burden of infection, incidence, mortality, and the cascade of care, and validated these data. FINDINGS: WHO received officially validated country-provided data from 130 countries or territories, and used partner-provided data for 70 countries or territories. We estimated that in 2019, globally, 295·9 million (3·8%) people were living with chronic hepatitis B virus (HBV) infection and 57·8 million (0·8%) people were living with chronic hepatitis C virus (HCV) infection. Globally, there were more than 3·0 million new infections with HBV and HCV and more than 1·1 million deaths due to the viruses in 2019. In 2019, 30·4 million (95% CI 24·3-38·0) individuals living with hepatitis B knew their infection status and 6·6 million (5·3-8·3) people diagnos...