From Waterloo to the Great Wall: A retrospective, multicenter study on the clinical practice and cultural attitudes in the management of premature ejaculation, in China

作者：Andrea Sansone, Jianlin Yuan, Guangdong Hou, Lei Zhang, Ming Gao, Zhe Zhang, Hui Jiang, Fu Wang, Jun Guo, Qiang Geng, Ming Wang, Xiansheng Zhang, Yu Xi, Yan Zhang, Jinchuan Liu, Yong‐Gang Duan, Dinesh Nagrale, Zhiguo Chen, Emmanuele A. Jannini, the MAPS‐GOSH (Marco Polo Study Group on Sexual Health) Other MAPS‐GOSH members, Elena Colonnello, Giacomo Ciocca, Erika Limoncin, Daniele Mollaioli, Xinlong Dun, Jiarui Yuan, Haocheng Lin, Hui Zhang · 发表于：Andrology · 年份：2023 · DOI：10.1111/andr.13403 · 被引用次数：20 · 研究领域：Sexual function and dysfunction studies、Sexuality, Behavior, and Technology、Genital Health and Disease

Premature ejaculation (PE), despite its wide prevalence, is largely underdiagnosed and undertreated. Being a multifactorial dysfunction with strong cultural characteristics, PE requires skillful attitudes in the psychosexological support, necessary to manage the patient's and the couple's expectations, as well as in the medical treatment. Dapoxetine is a short-acting selective serotonin reuptake inhibitor approved for use in lifelong and acquired PE in a number of countries. Opinions, not always generated by the evidence-based medicine, impacted the attitudes of Western andrologists, as a nocebo effect which produced a drug's Waterloo, characterized by low prescription rates much more built on the patients' and doctors' expectations than on costs, side effects, and efficacy. In the present study, we retrospectively reviewed real-life data from eight Andrology and Sexual Medicine Public Centers in China to assess the prevalence of PE among attending patients, its association with erectile dysfunction, its subtype, and the proposed treatments. In 2019, among 156,486 patients coming to the centers, 32,667 visits having PE as the chief complaint were performed (20.9%). Almost all patients received treatment prescriptions (32,641 patients, 99.92%); 23,273 patients came back for a follow-up visit in the subsequent 12 months (71.2% of those who initially received treatment). Dapoxetine, either alone or in combination with another therapy, was the most prevalent treatment, prescribed...