Multi-target antibacterial mechanism of ruthenium polypyridine complexes with anthraquinone groups against Staphylococcus aureus
作者:Li Jiang, Yuanyuan Ma, Yiman Chen, Mengcheng Cai, Zhixing Wu, Yanshi Xiong, Xuemin Duan, Xiangwen Liao, Jintao Wang · 发表于:RSC Medicinal Chemistry · 年份:2023 · DOI:10.1039/d2md00430e · 被引用次数:13 · 研究领域:Metal complexes synthesis and properties、Advanced biosensing and bioanalysis techniques、Antimicrobial agents and applications
was comparable to that of vancomycin. Mechanism exploration results showed that the antibacterial behavior is probably related with targeting of the bacterial cell membrane and inhibiting topoisomerase I.