Bioaccumulation Behavior and Human Health Risk of Polybrominated Diphenyl Ethers in a Freshwater Food Web of Typical Shallow Lake, Yangtze River Delta

作者：Bei Li, Juanheng Wang, Guocheng Hu, Xiaolin Liu, Yunjiang Yu, Dan Cai, Ping Ding, Xin Li, Lijuan Zhang, Chongdan Xiang · 发表于：International Journal of Environmental Research and Public Health · 年份：2023 · DOI：10.3390/ijerph20032671 · 被引用次数：10 · 研究领域：Toxic Organic Pollutants Impact、Effects and risks of endocrine disrupting chemicals、Environmental Toxicology and Ecotoxicology

BACKGROUND: Polybrominated diphenyl ethers (PBDEs) have been commonly found in aquatic ecosystems. Many studies have elucidated the bioaccumulation and biomagnification of PBDEs in seas and lakes, yet few have comprehensively evaluated the bioaccumulation, biomagnification, and health risks of PBDEs in shallow lakes, and there is still limited knowledge of the overall effects of biomagnification and the health risks to aquatic organisms. METHODS: In this study, a total of 154 samples of wild aquatic organism and environmental samples were collected from typical shallow lakes located in the Yangtze River Delta in January 2020. The concentrations of PBDEs were determined by an Agilent 7890 gas chromatograph coupled and an Agilent 5795 mass spectrometer (GC/MS) and the bioaccumulation behavior of PBDEs was evaluated in 23 aquatic organisms collected from typical shallow lakes of the Yangtze River Delta. Furthermore, their effects on human health were evaluated by the estimated daily intake (EDI), noncarcinogenic risk, and carcinogenic risk. RESULTS: The concentrations of ΣPBDE (defined as the sum of BDE-28, -47, -100, -99, -153, -154, -183, and -209) in biota samples ranged from 2.36 to 85.81 ng/g lipid weight. BDE-209, BDE-153 and BDE-47 were the major PBDE congeners. The factors affecting the concentration of PBDEs in aquatic organisms included dietary habits, species, and the metabolic debromination ability of the PBDE congeners. BDE-209 and BDE-47 were the strongest bioaccum...