Lessons on fruiting body morphogenesis from genomes and transcriptomes of Agaricomycetes

作者：László G. Nagy, Peter Jan Vonk, Markus Künzler, Csenge Földi, Máté Virágh, Robin A. Ohm, Florian Hennicke, B. Bálint, Á Csemetics, Botond Hegedüs, Zhaohua Hou, X.B. Liu, S. Nan, Manish Pareek, Neha Sahu, Benedek Szathmári, Tünde Varga, Hongli Wu, Xinyu Yang, Zsolt Merényi · 发表于：Studies in Mycology · 年份：2023 · DOI：10.3114/sim.2022.104.01 · 被引用次数：68 · 研究领域：Fungal Biology and Applications、Mycorrhizal Fungi and Plant Interactions、Biocrusts and Microbial Ecology

Fruiting bodies (sporocarps, sporophores or basidiomata) of mushroom-forming fungi ( Agaricomycetes ) are among the most complex structures produced by fungi. Unlike vegetative hyphae, fruiting bodies grow determinately and follow a genetically encoded developmental program that orchestrates their growth, tissue differentiation and sexual sporulation. In spite of more than a century of research, our understanding of the molecular details of fruiting body morphogenesis is still limited and a general synthesis on the genetics of this complex process is lacking. In this paper, we aim at a comprehensive identification of conserved genes related to fruiting body morphogenesis and distil novel functional hypotheses for functionally poorly characterised ones. As a result of this analysis, we report 921 conserved developmentally expressed gene families, only a few dozens of which have previously been reported to be involved in fruiting body development. Based on literature data, conserved expression patterns and functional annotations, we provide hypotheses on the potential role of these gene families in fruiting body development, yielding the most complete description of molecular processes in fruiting body morphogenesis to date. We discuss genes related to the initiation of fruiting, differentiation, growth, cell surface and cell wall, defence, transcriptional regulation as well as signal transduction. Based on these data we derive a general model of fruiting body development, whic...