Antimicrobial Resistance and Recent Alternatives to Antibiotics for the Control of Bacterial Pathogens with an Emphasis on Foodborne Pathogens

作者：Yosra A. Helmy, Khaled Taha-Abdelaziz, Hanan Abd El-Halim Hawwas, Soumya Ghosh, Samar Sami Alkafaas, Mohamed M. M. Moawad, Essa M. Saied, Issmat I. Kassem, Asmaa M. M. Mawad · 发表于：Antibiotics · 年份：2023 · DOI：10.3390/antibiotics12020274 · 被引用次数：188 · 研究领域：Antibiotic Resistance in Bacteria、Gut microbiota and health、Bacteriophages and microbial interactions

Antimicrobial resistance (AMR) is one of the most important global public health problems. The imprudent use of antibiotics in humans and animals has resulted in the emergence of antibiotic-resistant bacteria. The dissemination of these strains and their resistant determinants could endanger antibiotic efficacy. Therefore, there is an urgent need to identify and develop novel strategies to combat antibiotic resistance. This review provides insights into the evolution and the mechanisms of AMR. Additionally, it discusses alternative approaches that might be used to control AMR, including probiotics, prebiotics, antimicrobial peptides, small molecules, organic acids, essential oils, bacteriophage, fecal transplants, and nanoparticles.