The effects of acupuncture on clinical efficacy and steady-state visual evoked potentials in insomnia patients with emotional disorders: A randomized single-blind sham-controlled trial

作者：Leixiao Zhang, Yanli Deng, Ruting Hui, Yu Tang, Siyi Yu, Ying Li, Youping Hu, Ning Li · 发表于：Frontiers in Neurology · 年份：2023 · DOI：10.3389/fneur.2022.1053642 · 被引用次数：12 · 研究领域：Sleep and Wakefulness Research、Sleep and related disorders、Acupuncture Treatment Research Studies

The aim of this study was to observe the clinical effects and brain electrical potential changes following acupuncture in the treatment of insomnia patients with mood disorders. Ninety patients with insomnia who met the inclusion criteria were randomly divided into the active acupuncture group (AA group, n = 44) and sham acupuncture group (SA group, n = 46) at a ratio of 1:1. The primary outcome was the total score of the Pittsburgh Sleep Quality Index (PSQI), and the secondary outcomes were the total effective rate, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) scores, and values of steady-state visual evoked potentials (SSVEP). The two groups received acupuncture or sham acupuncture 10 times (2 weeks). Finally, the total PSQI scores of the AA group and SA group were significantly different ( p < 0.05) at 2 weeks (6.11 ± 2.33 vs. 10.37 ± 4.73), 6 weeks (6.27 ± 1.39 vs. 11.93 ± 3.07), 18 weeks (6.32 ± 2.84 vs. 11.78 ± 2.95) and 42 weeks (8.05 ± 3.14 vs. 12.54 ± 2.81). Further analysis found that AA group patients received acupuncture treatment at any age after the same effect ( p > 0.05). The SAS and SDS scores of the AA group were also significantly different from those of the SA group at each assessment time point ( p < 0.05). The total effective rate of the AA group was 81.82%, while that of the SA group was 30.43% ( p < 0.05). There was no significant difference between the AA group and SA group only in the brain potential...