Naringin mitigates LPS-induced intestinal barrier injury in mice

作者：Diaoyun Luo, Zhiqing Huang, Gang Jia, Hua Zhao, Guangmang Liu, Xiaoling Chen · 发表于：Food & Function · 年份：2023 · DOI：10.1039/d2fo03586c · 被引用次数：43 · 研究领域：Barrier Structure and Function Studies、Ginger and Zingiberaceae research、Gut microbiota and health

). However, the naringin treatment mitigated these effects induced by LPS. Taken together, our findings suggested that naringin attenuates LPS-induced intestinal barrier damage by inhibiting inflammatory factors and improving antioxidant function and intestinal tight junction, which might be mediated by activating the Nrf2 signaling and suppressing the TLR4/p38 MAPK/NF-κB signaling.