Comparison of coated and uncoated trace elements on growth performance, apparent digestibility, intestinal development and microbial diversity in growing sheep

作者：Jia Zhou, Yifan Ren, Wen Xiao, Shuangming Yue, Zhisheng Wang, Lizhi Wang, Quanhui Peng, Rui Hu, Huawei Zou, Yahui Jiang, Qionghua Hong, Xue Bai · 发表于：Frontiers in Microbiology · 年份：2022 · DOI：10.3389/fmicb.2022.1080182 · 被引用次数：16 · 研究领域：Ruminant Nutrition and Digestive Physiology、Selenium in Biological Systems、Moringa oleifera research and applications

The suitable supplement pattern affects the digestion and absorption of trace minerals by ruminants. This study aimed to compare the effects of coated and uncoated trace elements on growth performance, apparent digestibility, intestinal development and microbial diversity in growing sheep. Thirty 4-month-old male Yunnan semi-fine wool sheep were randomly assigned to three treatments ( n = 10) and fed with following diets: basal diet without adding exogenous trace elements (CON), basal diet plus 400 mg/kg coated trace elements (CTE, the rumen passage rate was 65.87%) and basal diet plus an equal amount of trace elements in uncoated form (UTE). Compared with the CON group, the average daily weight gain and apparent digestibility of crude protein were higher ( P < 0.05) in the CTE and UTE groups, while there was no difference between the CTE and UTE groups. The serum levels of selenium, iodine and cobalt were higher ( P < 0.05) in the CTE and UTE groups than those in the CON group, the serum levels of selenium and cobalt were higher ( P < 0.05) in the CTE group than those in the UTE group. Compared with the CON and UTE groups, the villus height and the ratio of villus height to crypt depth in duodenum and ileum were higher ( P < 0.05) in the CTE groups. The addition of trace minerals in diet upregulated most of the relative gene expression of Ocludin , Claudin-1 , Claudin-2 , ZO-1 , and ZO-2 in the duodenum and jejunum and metal ion transporters ( FPN...