Rh( iii )-catalyzed [4 + 1] cyclization of aryl substituted pyrazoles with cyclopropanols via C–H activation

作者：Wenxi Chen, Yan Mao, Min Wang, Fei Ling, Changchang Li, Zhangpei Chen, Jinzhong Yao · 发表于：Organic & Biomolecular Chemistry · 年份：2022 · DOI：10.1039/d2ob02001g · 被引用次数：15 · 研究领域：Catalytic C–H Functionalization Methods、Cyclopropane Reaction Mechanisms、Catalytic Alkyne Reactions

]isoindoles is described. The reaction features good functional group compatibility and a broad substrate scope with respect to both cyclization components with up to 84% yields. Mechanistic studies indicated that the C-H cleavage might be the rate-determining step in this transformation.