Dual degradation mechanism of GPX4 degrader in induction of ferroptosis exerting anti-resistant tumor effect

作者：Chao Wang, Cangxin Zheng, Han Wang, Sufang Shui, Hongwei Jin, Guoquan Liu, Fengrong Xu, Zhenming Liu, Liangren Zhang, Dan Sun, Ping Xu · 发表于：European Journal of Medicinal Chemistry · 年份：2022 · DOI：10.1016/j.ejmech.2022.115072 · 被引用次数：54 · 研究领域：Peptidase Inhibition and Analysis、Protein Degradation and Inhibitors、Multiple Myeloma Research and Treatments