Ultrasonography Comparison of Diaphragm Morphological Structure and Function in Young and Middle-Aged Subjects with and without Non-Specific Chronic Low Back Pain: A Case-Control Study

作者：Wenwu Xiao, Fuming Zheng, Ke Dong, Zhuangfu Wang, Yao Zu, Chuhuai Wang · 发表于：Pain Research and Management · 年份：2022 · DOI：10.1155/2022/7929982 · 被引用次数：10 · 研究领域：Musculoskeletal pain and rehabilitation、Myofascial pain diagnosis and treatment、Fibromyalgia and Chronic Fatigue Syndrome Research

Background. It is reported that impaired postural control in patients with non-specific chronic low back pain (NCLBP) was associated with “core” trunk muscle incoordination. However, as the diaphragm is an important component of the “core” deep trunk muscle group, we still know little about the potential relationship between diaphragm dysfunction and NCLBP. Objectives. This case-control study is intended to investigate the changes of diaphragm morphological structure and function in young and middle-aged subjects with and without NCLBP by ultrasound evaluation and its possible validity in predicating the occurrence of NCLBP. Methods. 31 subjects with NCLBP (NCLBP group) and 32 matched healthy controls (HC group) were enrolled in this study. The diaphragm thickness at the end of inspiration (Tins) or expiration (Texp) during deep breathing was measured through B-mode ultrasound, and the diaphragm excursion (Texc) was estimated at deep breathing through M-mode ultrasound. The diaphragm thickness change rate (Trate) was calculated by the formula: T r a t e = T i n s − T exp / T exp × 100 % . Results. Compared with the HC group, the NCLBP group had a significant smaller degree of Tins (t = −3.90, P < 0.001 ), Texp (Z = −2.79, P = 0.005 ), and Trate (t = −2.03, P = 0.047 ). However, there was no statistical difference in Texc between the two groups (t = −1.42, P = 0.161 ). The binary logistic regression a...