Epidemiology of autism spectrum disorders: Global burden of disease 2019 and bibliometric analysis of risk factors

作者：Yang-An Li, Ze‐Jian Chen, Xiaodan Li, Minghui Gu, Nan Xia, Gong Chen, Zhao-Wen Zhou, Gvzalnur Yasin, Haoyu Xie, Xiupan Wei, Yali Liu, Xiaohua Han, Min Lu, Jiang Xu, Xiaolin Huang · 发表于：Frontiers in Pediatrics · 年份：2022 · DOI：10.3389/fped.2022.972809 · 被引用次数：68 · 研究领域：Autism Spectrum Disorder Research、Advanced Technologies and Applied Computing、Cancer Research and Treatment

Background: To explore the geographical pattern and temporal trend of autism spectrum disorders (ASD) epidemiology from 1990 to 2019, and perform a bibliometric analysis of risk factors for ASD. Methods: In this study, ASD epidemiology was estimated with prevalence, incidence, and disability-adjusted life-years (DALYs) of 204 countries and territories by sex, location, and sociodemographic index (SDI). Age-standardized rate (ASR) and estimated annual percentage change (EAPC) were used to quantify ASD temporal trends. Besides, the study performed a bibliometric analysis of ASD risk factors since 1990. Publications published were downloaded from the Web of Science Core Collection database, and were analyzed using CiteSpace. Results: Globally, there were estimated 28.3 million ASD prevalent cases (ASR, 369.4 per 100,000 populations), 603,790 incident cases (ASR, 9.3 per 100,000 populations) and 4.3 million DALYs (ASR, 56.3 per 100,000 populations) in 2019. Increases of autism spectrum disorders were noted in prevalent cases (39.3%), incidence (0.1%), and DALYs (38.7%) from 1990 to 2019. Age-standardized rates and EAPC showed stable trend worldwide over time. A total of 3,991 articles were retrieved from Web of Science, of which 3,590 were obtained for analysis after removing duplicate literatures. "Rehabilitation", "Genetics & Heredity", "Nanoscience & Nanotechnology", "Biochemistry & Molecular biology", "Psychology", "Neurosciences", and "Environmental Sciences" were the hotspo...