Effects of exercise by type and duration on quality of life in patients with digestive system cancers: A systematic review and network meta-analysis

作者：Chen-Qi Li, Yuan‐Chen Wang, Shuqun Shen, Yanli Zhang, Jieqiong Zhao, Wenbin Zou, Ruiliang Ge · 发表于：Journal of sport and health science/Journal of Sport and Health Science · 年份：2022 · DOI：10.1016/j.jshs.2022.12.008 · 被引用次数：28 · 研究领域：Cancer survivorship and care、Oral health in cancer treatment、Nutrition and Health in Aging

BACKGROUND: There is scant evidence regarding the effects of exercise type and duration on quality of life (QoL) in digestive system cancer (DSC) survivors. We aim to investigate the optimal type and duration of exercise to improve QoL for DSC survivors through a systematic review and network meta-analysis. METHODS: A systematic literature search of PubMed, Embase, and Web of Science was performed. Eligibility for study inclusion was limited to studies that were randomized controlled trials involving all kinds of exercise in adult patients with DSCs, and the comparator was in standard care or other types of exercise. The primary outcome was QoL, including general health, physical health, mental health, and role function. Secondary outcomes included cancer-related symptoms such as fatigue, insomnia, depression, anxiety, and duration of hospital stay. The network meta-analyses were performed using a random-effect model. RESULTS: The analysis included 32 eligible articles and a total of 2558 participants. Our primary outcome indicated that short-term aerobic exercise significantly enhanced general health (standardized mean difference (SMD) = 0.66, 95% credible intervals (CrIs): 0.05 to 1.30), and also contributed to a better mental health (SMD = 0.38, 95%CrI: -0.05 to 0.81) and role function (SMD = 0.48, 95%CrI: -0.27 to 1.20). Although without significant changes, short-term resistance exercise tended to increase the physical health of patients with DSCs (SMD = 0.69, 95%CrI: -0...