Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology

作者：Mi Qin, Qianqian Huang, Xin Yang, Lu Yu, Yong Tang, Chunxiang Zhang, Dalian Qin, Wenjun Zou, Junzhu Deng, Jian Liu, Haiyang Hu, Long Wang, Anguo Wu, Jianming Wu · 发表于：Chinese Medicine · 年份：2022 · DOI：10.1186/s13020-022-00694-5 · 被引用次数：16 · 研究领域：Ethnobotanical and Medicinal Plants Studies、Chemical synthesis and alkaloids、Phytochemistry and Biological Activities

BACKGROUND: Taxillus chinensis (DC.) Danser (T. chinensis), known as "Sangjisheng" in Chinese, is a member of the family Loranthaceae, with the traditional functions of "dispelling wind dampness, strengthening bones and muscles, and preventing miscarriage". Since Eastern Han dynasty, it has been used for the treatment of rheumatoid arthritis, arthralgia, threatened abortion, and hypertension. Nowadays, T. chinensis is included in the 2020 Edition of the Chinese Pharmacopoeia as Taxilli Herba. The purpose of this review is to summarize the latest research on T. chinensis in recent years, and make critical comments, so as to provide reference for the clinical application and modern research of T. chinensis. MAIN BODY: In this review, we summarize the botany, traditional uses, and research advances in the phytochemistry and pharmacological effects of T. chinensis. Its toxicity has also been discussed. The published literature on current pharmacological and toxicological data has also been assessed. To date, approximately 110 compounds, including flavonoids, phenolic acids, phenylpropanoids, tannins, glycosides, amino acids, and nucleosides, have been identified in T. chinensis. Flavonoids are considered the most vital bioactive ingredients in T. chinensis. Pharmacological studies have demonstrated that T. chinensis possesses anti-inflammatory, antioxidant, anticancer, antimicrobial, antiviral, diuretic, antihypertensive, antihyperglycemic, and other properties. CONCLUSION: Curre...