Benefits of successful percutaneous coronary intervention in chronic total occlusion patients with diabetes

作者：Shuai Zhao, Yan Chen, Qingyi Wang, Boda Zhu, Zhihong Wei, Ziwei Wang, Jiayi Wang, Yiming Zou, Wentao Hu, Cheng Liu, Tiantong Yu, Peng Han, Yang Li, Huan Wang, Chenhai Xia, Qiling Liu, Wei Wang, Haokao Gao, Chengxiang Li, Kun Lian · 发表于：Cardiovascular Diabetology · 年份：2022 · DOI：10.1186/s12933-022-01708-0 · 被引用次数：9 · 研究领域：Coronary Interventions and Diagnostics、Cardiac Valve Diseases and Treatments、Acute Myocardial Infarction Research

BACKGROUND: Diabetes was commonly seen in chronic total occlusion (CTO) patients but data regarding the impact of successful percutaneous coronary intervention (PCI) on clinical outcome of CTO patients with diabetes was controversial. And importantly, no studies have compared quality of life (QOL) after CTO-PCI in patients with and without diabetes. METHODS: Consecutive patients undergoing elective CTO-PCI were prospectively enrolled from Apr. 2018 to May 2021. Patients were subdivided into 2 groups: Diabetes and No Diabetes. Detailed baseline characteristics, assessment of symptoms and QOL, angiographic and procedural details, in-hospital complications, and 1 month and 1 year follow-up data were collected. These data were analyzed accordingly for risk predictors of clinical outcome in patients who have diabetes and received successful CTO-PCI. RESULTS: A total of 1076 patients underwent CTO-PCI attempts. Diabetes was present in 374 (34.76%) patients, who had more hypertension, previous PCI and stroke. Regarding the coronary lesions, diabetic patients suffered more LCX lesion, multivessel disease, number of lesions per patient, blunt stump, calcification and higher J-CTO score (p < 0.05). In-hospital major adverse cardiac event (MACE) (4.13% vs. 5.35%; p = 0.362) was similar in the two groups. At 1 month and 1 year follow-up after successful CTO-PCI, the incidence of MACE and all-cause mortality were also similar in the two groups (p > 0.05). Number of lesions per patient was...