Risk Factors for Postoperative Cerebrospinal Fluid Leakage Following Retrosigmoid Approach Surgery for Vestibular Schwannoma

作者：Zuli Hu, YueHua Song, Gang Liao, Deliang Wang, Zhangjie Yin, Shan Xu, Chun liang Wang · 发表于：Research Square · 年份：2022 · DOI：10.21203/rs.3.rs-2297720/v1 · 被引用次数：1 · 研究领域：Meningioma and schwannoma management、Head and Neck Surgical Oncology、Neurofibromatosis and Schwannoma Cases

Abstract Objective The purpose of this study was to investigate factors associated with postoperative CSF leakage. Methods The study included 441 patients who underwent a retrosigmoid approach for opening the internal auditory canal posterior wall during complete resection of Vestibular Schwannoma at the department of neurosurgery in the First Affiliated Hospital of Nanchang University between May 2012 and May 2022. We conducted a comparative analysis within fifteen days of surgery between patients with and without postoperative CSF leakage, which involved statistical factors, such as age, sex, recurrence, tumor size, tumor site, petrous apex pneumatization, internal auditory canal posterior wall pneumatization, and operation time. Results Our study showed that ten (2.27%) of 441 patients exhibited a postoperative CSF leak. Pneumatization of the IAC posterior wall showed statistical significance in postoperative CSF leakage (p < 0.01). Conclusions Pneumatization of the internal auditory canal posterior wall was found to be a risk factor for postoperative CSF leakage following the retrosigmoid approach.