Low dimensional nanomaterials for treating acute kidney injury

作者：Yuanpeng Nie, Liying Wang, Xinru You, Xiaohua Wang, Jun Wu, Zhihua Zheng · 发表于：Journal of Nanobiotechnology · 年份：2022 · DOI：10.1186/s12951-022-01712-2 · 被引用次数：22 · 研究领域：Acute Kidney Injury Research、Graphene and Nanomaterials Applications、Anesthesia and Neurotoxicity Research

Acute kidney injury (AKI) is one of the most common severe complications among hospitalized patients. In the absence of specific drugs to treat AKI, hemodialysis remains the primary clinical treatment for AKI patients. AKI treatment has received significant attention recently due to the excellent drug delivery capabilities of low-dimensional nanomaterials (LDNs) and their unique therapeutic effects. Diverse LDNs have been proposed to treat AKI, with promising results and the potential for future clinical application. This article aims to provide an overview of the pathogenesis of AKI and the recent advances in the treatment of AKI using different types of LDNs. In addition, it is intended to provide theoretical support for the design of LDNs and implications for AKI treatment.