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Structure-based design of bitopic ligands for the µ-opioid receptor

作者:Abdelfattah Faouzi, Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu, Michael J. Robertson, Manish K. Madasu, Amal El Daibani, Balázs R. Varga, Tiffany Zhang, Claudia H. Ruiz, Shan Liu, Jin Xu, Kevin Appourchaux, Samuel T. Slocum, Shainnel O. Eans, Michael D. Cameron, Ream Al‐Hasani, Ying‐Xian Pan, Bryan L. Roth, Jay P. McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K. Kobilka, Susruta Majumdar · 发表于:Nature · 年份:2022 · DOI:10.1038/s41586-022-05588-y · 被引用次数:133 · 研究领域:Receptor Mechanisms and Signaling、Neuropeptides and Animal Physiology、Pharmacological Receptor Mechanisms and Effects