Demographic and Clinical Characteristics of Multiple Myeloma Patients in Latin America

作者：Vania Tietsche de Moraes Hungria, Damila Cristina Trufelli, Jaqueline Saes, Karina Nakajima, Lays Paulino Leonel, Rafael Dezen Gaiolla, Kenny Gálvez, Guillermina Remaggi, Rosane Bittencourt, Ângelo Maiolino, Natalia Paola Schutz, Guillermo Quintero · 发表于：Blood · 年份：2022 · DOI：10.1182/blood-2022-163763 · 被引用次数：1 · 研究领域：Multiple Myeloma Research and Treatments

Background: Multiple myeloma (MM) is characterized by uncontrolled proliferation of plasma cells. This condition accounts for 1% of all cancers and 13% of all hematologic malignancies (HMs). In Latin America there is a relative paucity of real-world data of MM patients. Therefore, the objective of this study is to describe the demographic and clinical characteristics of multiple myeloma patients in Latin America. Methods: This is an ongoing, noninterventional, multicenter, registry study. Patients diagnosed with MM between 01 January 2016 and 30 June 2021, age ≥ 18 years were enrolled and will be followed until death or the end of study (set for 30 June 2022). For this interim analysis the demographic and clinical data of MM patients in a real-world setting in five Latin American countries, Argentina, Brazil, Mexico, Colombia, and Panama, were assessed. The retrospective data are being abstracted from patient's medical records. All statistical analyses were descriptive. Results: From a total of 1076 enrolled patients, 984 were assessed (Argentina= 287; Brazil= 428; Colombia= 253; Mexico= 13; Panama= 3). 64.9% of the patients have private insurance coverage, and 35.1% belongs to the public treatment system. The median age at diagnosis was 63 years and a similar distribution between male (49.3%) and female (50.7%) was observed. The majority of the patients (78.7%) presented at least one comorbidity, with hypertension (62.2%) and diabetes (21.1%) the most common medical conditio...