Discovery of novel 7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidines as ATR inhibitors based on structure-based drug design

作者：Yinliang Qi, Kun Wang, Bin Long, Hao Yue, Yongshuo Wu, Dexiao Yang, Minghui Tong, Xuan Shi, Yunlei Hou, Yanfang Zhao · 发表于：European Journal of Medicinal Chemistry · 年份：2022 · DOI：10.1016/j.ejmech.2022.114945 · 被引用次数：16 · 研究领域：DNA Repair Mechanisms、Cancer therapeutics and mechanisms、Cell death mechanisms and regulation