Prolonged breastfeeding, sugar consumption and dental caries at 2 years of age: A birth cohort study

作者：Jenny Abanto, Jéssica Mayumi Maruyama, Emanuella Pinheiro, Alícia Matijasevich, José Leopoldo Ferreira Antunes, Marcelo Bönecker, Marly Augusto Cardoso, the MINA‐Brazil Study Group · 发表于：Community Dentistry And Oral Epidemiology · 年份：2022 · DOI：10.1111/cdoe.12813 · 被引用次数：19 · 研究领域：Dental Health and Care Utilization、Breastfeeding Practices and Influences、Oral microbiology and periodontitis research

OBJECTIVES: Previous cohort studies have found a positive association between prolonged breastfeeding (≥12 months) on dental caries, but few of them analysed the mediated effect of sugar consumption on this association. This study investigated whether prolonged breastfeeding is a risk factor for caries at 2-year follow-up assessment (21-27 months of age) and whether this effect is mediated by sugar consumption. METHODS: A birth cohort study was performed in the Brazilian Amazon (n = 800). Dental caries was assessed using the dmf-t index. Prolonged breastfeeding was the main exposure. Data on baseline covariables and sugar consumption at follow-up visits were analysed. We estimated the OR for total causal effect (TCE) and natural indirect effect (NIE) of prolonged breastfeeding on dental caries using the G-formula. RESULTS: The prevalence of caries was 22.8% (95% CI: 19.8%-25.8%). Children who were breastfed for 12-23 months (TCE = 1.13, 95% CI: 1.05-1.20) and for ≥24 months (TCE = 1.27, 95% CI: 1.14-1.40) presented a higher risk of caries at age of 2 years than those breastfed <12 months. However, this risk was slightly mediated by a decreased frequency of sugar consumption at age of 2 years only for breastfeeding from 12 to 23 months (NIE; OR = 0.95, 95% CI: 0.91-0.97). CONCLUSIONS: In this study, the effect of prolonged breastfeeding on the increased risk of dental caries was slightly mediated by sugar consumption. Early feeding practices for caries prevention and promoting...